ТРИМЕТИЛАМИН-Н-ОКСИД КАТО МАРКЕР НА СИСТЕМНО ВЪЗПАЛЕНИЕ ПРИ АВТОИМУНЕН ТИРЕОИДИТ НА ХАШИМОТО. (Bulgarian)

TRIMETHILAMINE-N-OXIDE AS A MARKER OF SYSTEMIC INFLAMMATION IN HASHIMOTO’S THYROIDITIS. (English)

Diet for many years has been considered a general health determinant. Recent research shows a connection between gut microbiota composition that is shaped by our diet and lifestyle diseases. Plasma trimethylamine N-oxide (TMAO) originates from gut bacteria metabolism of dietary l-carnitine, betaine, and choline. A number of studies suggest a positive correlation between elevated plasma trimethylamine N-oxide levels and a risk for cardiovascular diseases, diabetes, and cancer. Recent experimental and clinical evidence shows that TMAO may serve as a diagnostic and prognostic marker of many pathologic conditions. Therefore, rapid determination of serum TMAO concentration is of clinical interest. [ABSTRACT FROM AUTHOR]

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