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*open the 2nd and 4th Saturday
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West Ashley Library
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Wando Mount Pleasant Library
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The original scores of traditional Chinese medicine constitutions are risk and diagnostic factors in middle‐aged and older adults with sarcopenia.
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- Author(s): Nie, Xin; Wang, Chi; Zhang, He; Liu, Qianhui; Hou, Lisha; Deng, Yiping; Ye, Wenbin; Yue, Jirong; He, Yong
- Source:
Aging Medicine; Jun2024, Vol. 7 Issue 3, p334-340, 7p- Subject Terms:
RISK assessment; CHINESE medicine; CROSS-sectional method; LIFESTYLES; SELF-evaluation; MEDICAL history taking; PREDICTIVE tests; RESEARCH funding; RECEIVER operating characteristic curves; T-test (Statistics); QUESTIONNAIRES; FUNCTIONAL status; DESCRIPTIVE statistics; MULTIVARIATE analysis; MANN Whitney U Test; CHI-squared test; HUMAN constitution; CLINICAL pathology; ENERGY metabolism; STATISTICS; SOCIODEMOGRAPHIC factors; SARCOPENIA; REGRESSION analysis; OLD age; MIDDLE age - Source:
- Additional Information
- Subject Terms:
- Abstract: Objective: Sarcopenia is a geriatric syndrome that occurs with age and is characterized by a gradual decline in muscle mass, power, and functionality. It serves as a prominent contributor to frailty, disability, and mortality among older individuals. Currently, no standardized global guidelines exist for the diagnosis of sarcopenia. This study aimed to establish the correlation between sarcopenia and the constitutions of traditional Chinese medicine (TCM), considering the connection between physical functioning and sarcopenia. Methods: A total of 1441 participants in this study were diagnosed with sarcopenia. The Asian Working Group for Sarcopenia (AWGS) proposed a sarcopenia definition algorithm. To determine the constitution of each participant, classification and determination standards were used in traditional Chinese medicine. This study evaluated the demographics, lifestyles, and self‐reported medical history of individuals diagnosed with sarcopenia through a self‐administered questionnaire. The constitution of the participants was determined using TCM classification and determination standards. Subsequently, we analyzed the results of univariate analysis and multivariate regression and constructed a receiver operating characteristic (ROC) curve. Results: Participants who were diagnosed with sarcopenia had substantially lower original Neutral constitution scores (P < 0.050). In comparison to those without sarcopenia, individuals with sarcopenia exhibited notably elevated original Qi‐deficiency, Yang‐deficiency, Yin‐deficiency, Blood‐stagnation, and Qi‐stagnation scores in contrast to those in the healthy group (P < 0.050). The identified risk factors associated with sarcopenia included the following: Neutral (OR = 0.903), Qi‐deficiency (in males, OR = 1.126), Yang‐deficiency (OR = 1.062), Phlegm‐dampness (in males, OR = 0.833), and Blood‐stagnation (in females, OR = 1.089). The highest area under the curve (AUC) was observed for the original neutral constitution score, followed by the Yang‐deficiency and blood‐stagnation scores (0.644, 0.613, and 0.611, respectively). Additionally, the AUC for the combined original scores of all nine constitutions among males reached 0.778. Conclusions: In this cross‐sectional study of older people with higher original Qi‐deficiency, Yin deficiency, Yang‐deficiency, Blood‐stagnation, and Qi‐stagnation were associated with sarcopenia. Notably, various TCM constitutions are significantly linked to sarcopenia. There was a significant occurrence of various body constitution types among individuals diagnosed with sarcopenia. The mixture of the nine original constitution scores exhibited good diagnostic performance for sarcopenia in males. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Aging Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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