Findings from Tohoku University Hospital Update Understanding of Biomarkers (Analysis of Metabolic Changes In Endogenous Metabolites and Diagnostic Biomarkers for Various Diseases Using Liquid Chromatography and Mass Spectrometry).

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  • Source:
    Health & Medicine Week; 7/12/2024, p1964-1964, 1p
  • Additional Information
    • Abstract:
      A report from Tohoku University Hospital in Sendai, Japan discusses the analysis of metabolic changes in endogenous metabolites and diagnostic biomarkers for various diseases using liquid chromatography and mass spectrometry. The researchers have developed LC/MS/MS methods for metabolites and applied them to disease-related samples. They have identified useful biomarkers for Niemann-Pick disease type C, developed analysis methods for glioma patients, searched for biomarkers for renal cell carcinoma, and analyzed liver cholesterol metabolites for non-alcoholic steatohepatitis. The researchers aim to continue adding value to clinical practice through their analytical chemistry methodology. [Extracted from the article]
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