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Wando Mount Pleasant Library
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Village Library
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Folly Beach Library
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*open the 2nd and 4th Saturday
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Dorchester Road Library
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Pilot Trial Results of Mlambe: An Economic and Relationship-Strengthening Intervention to Address Heavy Drinking and Adherence to Antiretroviral Therapy in Malawi.
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- Author(s): Conroy, Amy A.; Hahn, Judith A.; Neilands, Torsten B.; Darbes, Lynae A.; Tebbetts, Scott; Mulauzi, Nancy; Mkandawire, James; Ssewamala, Fred M.
- Source:
AIDS & Behavior; Jul2024, Vol. 28 Issue 7, p2296-2306, 11p- Subject Terms:
PREVENTION of alcoholism; PATIENT compliance; INCOME; RESEARCH funding; SATISFACTION; VIRAL load; SPOUSES; PILOT projects; STATISTICAL sampling; HIV infections; TREATMENT effectiveness; RANDOMIZED controlled trials; DESCRIPTIVE statistics; CONTROL groups; PRE-tests & post-tests; ECONOMIC impact; FINANCIAL management; MARITAL status; RESEARCH; ALCOHOL drinking; DRUGS; COMPARATIVE studies; AIDS - Source:
- Additional Information
- Subject Terms:
- Abstract: We evaluated the feasibility, acceptability, and preliminary efficacy of an economic and relationship-strengthening intervention to reduce heavy alcohol use among couples living with HIV in Malawi (Mlambe). Mlambe consisted of training on financial literacy and relationship skills, combined with 1:1 matched savings accounts to invest in an income-generating activity. In a randomized controlled trial, we compared Mlambe to enhanced usual care (EUC). We enrolled 78 married couples having a partner on antiretroviral therapy (ART) who reported heavy alcohol use based on the AUDIT-C. Using targets of 75%, primary outcomes included retention rates at 10 and 15-months, session attendance rates, and satisfaction with Mlambe. Exploratory outcomes were heavy alcohol use (AUDIT-C and/or PEth positive), number of drinking days in the past month, AUDIT-C score, optimal adherence to ART (95% or higher), and viral suppression. We exceeded our targets for feasibility and acceptability metrics. Retention rates were 96% at 15-months. Session attendance and satisfaction levels were both 100%. From baseline to 15-months, Mlambe participants reported decreases in mean number of drinking days (from 6.8 to 2.1) and AUDIT-C scores (from 7.5 to 3.1); while ART adherence rates improved across the same period (from 63.2 to 73.9%). Participants in Mlambe, as compared to those in EUC, had lower rates of heavy alcohol use (89.5% vs. 97.2%) and higher rates of viral suppression (100% vs. 91.9%) at 10-months. Differences between arms were not statistically significant in this small pilot study. Mlambe was highly feasible and acceptable, and shows promise for reducing heavy alcohol use and viral non-suppression among couples with HIV in a larger efficacy study. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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