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Phone: (843) 766-6635
Wando Mount Pleasant Library
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9 a.m. - 8 p.m.
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Does young feces make the elderly live better? Application of fecal microbiota transplantation in healthy aging.
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- Author(s): YUANYUAN LIAO; XINSI LI; QIAN LI; YIZHONG WANG; XIUJUN TAN; TING GONG
- Source:
Biocell; 2024, Vol. 48 Issue 6, p873-887, 15p- Subject Terms:
- Source:
- Additional Information
- Abstract: As we are facing an aging society, anti-aging strategies have been pursued to reduce the negative impacts of aging and increase the health span of human beings. Gut microbiota has become a key factor in the anti-aging process. Modulation of gut microbiota by fecal microbiota transplantation (FMT) to prevent frailty and unhealthy aging has been a hot topic of research. This narrative review summarizes the benefits of FMT for health span and lifespan, brains, eyes, productive systems, bones, and others. The mechanisms of FMT in improving healthy aging are discussed. The increased beneficial bacteria and decreased pathological bacteria decreased gut permeability and systemic inflammation, increased short-chain fatty acid (SCFA) and SCFA-producing bacteria, and other factors are listed as mechanisms of FMT to improve healthy aging. The points that need to be considered to ensure the optimal outcomes of FMT are also discussed, such as recipients' age, sex, genetic background, and gut microbiota after FMT. Although this field is still in its infancy, it has shown that FMT has great potential to improve healthy aging. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Biocell is the property of Tech Science Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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