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Risk predictors of glycaemic control in children and adolescents with type 1 diabetes: A systematic review and meta‐analysis.
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- Author(s): Gangqiang, Gao; Hua, Chen; Hongyu, Sun
- Source:
Journal of Clinical Nursing (John Wiley & Sons, Inc.). Jul2024, Vol. 33 Issue 7, p2412-2426. 15p. - Source:
- Additional Information
- Subject Terms: TYPE 1 diabetes; RISK assessment; MEDICAL information storage & retrieval systems; STATISTICAL models; BODY mass index; GLYCOSYLATED hemoglobin; PREDICTION models; RESEARCH funding; GLYCEMIC control; SEX distribution; EICOSAPENTAENOIC acid; SOCIOECONOMIC status; META-analysis; DESCRIPTIVE statistics; INSULIN pumps; ATTITUDES of mothers; LEUCINE; DIABETIC acidosis; FAMILY history (Medicine); SYSTEMATIC reviews; MEDLINE; RACE; ODDS ratio; ONLINE information services; DATA analysis software; CONFIDENCE intervals; CONSCIENCE; DIETARY carbohydrates; FAMILY support; BLOOD sugar monitoring; SOCIAL classes; PATIENT aftercare
- Abstract: Objectives: To conduct systematic evaluation of the risk predictors of glycaemic control in children and adolescents with type 1 diabetes mellitus. Methods: Cohort studies on risk predictors of glycaemic control in children and adolescents with type 1 diabetes were retrieved from CNKI, PubMed, Web of Science, Embase databases, etc. from the construction of the repository to 3 February 2023. Literature screening was conducted according to inclusion and exclusion criteria, then data extraction of region, sample size, age, follow‐up time, risk predictors, outcome indicators, etc., and quality evaluation of The Newcastle‐Ottawa Scale were conducted by two researchers while the third researcher makes decisions if there are disagreements. Finally, Revman5.4 and StataMP17 were used for meta‐analysis. Results: A total of 29 studies were included, and the results showed that insulin pump [Weighed mean difference (WMD) = −.48, 95% CI (−.73, −.24), p <.01], high‐frequency sensor monitoring, early use of insulin pumps, prospective follow‐up male, white race, large body mass index‐standardised scoring, conscientiousness, agreeableness of mothers, eicosapentaenoic acid, leucine and protein (p <.05) were beneficial for reducing HbA1c levels in children and adolescents with diabetes. Ketoacidosis [WMD =.39, 95% CI (.28,.50), p <.01], selective admission, higher HbA1c level at one time (p <.01), higher glutamate decarboxylase antibody at 1 month after diagnosis, lower socio‐economic status, non‐living with biological parents, non‐two‐parent family, family disorder, family history of diabetes and high carbohydrate intake (p <.05) increased HbA1c levels in children and adolescents with diabetes. Conclusion: For children and adolescents with type 1 diabetes mellitus, the use of insulin pump, high‐frequency sensor monitoring, prospective follow‐up, good family support and reasonable diet are conducive to blood glucose control, while selective admission and DKA are not. Disease characteristics and demographic characteristics of children are closely related to subsequent blood glucose control, and the relationship between diagnosis age and blood glucose control needs to be further explored. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of Clinical Nursing (John Wiley & Sons, Inc.) is the property of John Wiley & Sons, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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