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Comparative Assessment of Total Antioxidant Capacity of Unstimulated Saliva Which Can Reflect the Oxidative Stress between Autism Children and Normal Children.
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- Author(s): Sundaram, Manikandan; Kumarasamy, Baskaran; Subbian, Kavitha P.; Perumal, Mohan Kumar; Balu, Kiruthika; Manikandan, Saranya
- Source:
Journal of Pharmacy & Bioallied Sciences; 2024 Supplement, Vol. 16, pS1811-S1814, 4p- Subject Terms:
- Source:
- Additional Information
- Subject Terms:
- Abstract: Aim: To assess the level of total antioxidant capacity (TAC) in the unstimulated saliva of autism children and normal children. Methods: A total of 60 children participated in the study (autism children--30; normal children--30) in the age-group of 7-14 years, at a Special Needs Children's Home in Salem district. Both groups were further subdivided into subgroups of 15 children each (caries-free and caries-active). All children were given instructions regarding saliva sample collection, and unstimulated saliva samples were collected in sterile cryovials and transported to the laboratory at 4°C, where the TAC of saliva was evaluated using the spectrophotometric assay. Results: TAC of autism children was comparable to that of normal children due to personal care and improved diet. TAC was increased in caries-active children when compared to caries-free children in both groups. When comparing the mean values of TAC in caries-active and caries-free children of both groups, it was not statistically significant. So, from the above results, it can be assumed that the diet, age, and caries activity have a definitive influence on the TAC level of saliva. Conclusion: Personal hygiene, diet, age, and caries activity have a definitive influence on the level of TAC in saliva. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of Pharmacy & Bioallied Sciences is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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