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Predictive value of clinical symptoms for COVID-19 diagnosis in young adults.
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- Author(s): Kunkel, Deborah; Stuenkel, Mackenzie; Sivaraj, Laksika B.; Colenda, Christopher C.; Pekarek, Lesslie; Rennert, Lior
- Source:
Journal of American College Health. May/Jun2024, Vol. 72 Issue 4, p1006-1009. 4p. - Source:
- Additional Information
- Subject Terms: PREDICTIVE tests; PUBLIC health surveillance; MANDATORY medical testing; MYALGIA; RESEARCH funding; SHIVERING; COVID-19 testing; RETROSPECTIVE studies; FEVER; DESCRIPTIVE statistics; SURVEYS; ODDS ratio; ASSOCIATIONS, institutions, etc.; EPIDEMICS; COLLEGE students; SMELL disorders; AGEUSIA; PUBLIC health; CONFIDENCE intervals; COVID-19; SOCIAL isolation; SARS-CoV-2; ADULTS
- Abstract: Objective: Assessment of predictive values of clinical symptoms for COVID-19 diagnosis in young adults. Participants: Nonresidential university students (ages 18–25) participating in surveillance testing and mandatory symptom survey between 9/9/2020 and 11/25/2020. Methods: Retrospective study of test results and symptom survey data. Results: Among 6,489 individuals, 288 (4.4%) tested positive for COVID-19, 90 (31.3%) of whom reported symptoms. COVID-19 prevalence among individuals reporting and not reporting symptoms was 17.2% and 3.3%, respectively. The four symptoms with highest positive predictive values (PPVs) were smell/taste loss (PPV = 38.5%), chills (PPV = 31.5%), muscle/joint pain (PPV = 26.0%), and fever (PPV = 25.9%). Conclusions: Institutions should emphasize COVID-19 risk for highly predictive symptoms in public health messaging to inform individuals on when to seek testing or self-isolation. However, low COVID-19 diagnostic accuracy of clinical symptoms and the high pre-symptomatic/asymptomatic rate (69%) highlight the limitations of voluntary testing strategies employed by higher education institutions during the original strain of SARS-CoV-2. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of American College Health is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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