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Giant Ganglioneuroma of the Lumbar Spine: A Rare Cause of Radiculopathy.
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- Author(s): Altalhi, Lina1 (AUTHOR); Alayyaf, Abdulaziz2 (AUTHOR); Bin-Mahfooz, Mohammed3 (AUTHOR); Alhumoudi, Duaa4 (AUTHOR); Alkhaibary, Ali3,5,6 (AUTHOR); AlSufiani, Fahd4,5,7 (AUTHOR); Alassiri, Ali H.4,5,7 (AUTHOR); AlQahatani, Saad3,5,6 (AUTHOR); Khairy, Sami3,5,6 (AUTHOR); Alkhani, Ahmed3,5,6 (AUTHOR)
- Source:
Case Reports in Surgery. 5/23/2024, Vol. 2024, p1-4. 4p.
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- Additional Information
- Abstract:
Background. Ganglioneuroma (GN) is a rare, benign tumor that originates from neural crest cells and can potentially affect any anatomical site within the sympathetic nervous system. Typically, GNs are more frequently reported in children and young adults, with a slightly higher prevalence in females. We are reporting a rare case of a giant lumbar spine ganglioneuroma by outlining the clinical presentation, radiological finding, management, and outcome. Case Description. A 37-year-old female presented with low back pain radiating to the right lower limb for few years. Neurological examination revealed bilateral lower limb hyperreflexia (+3). Lumbar spine CT and MRI revealed a right paravertebral soft tissue lesion with heterogeneous signal intensity and enhancement at L1 to L3. The patient underwent complete resection of the lesion via a retroperitoneal approach. The surgery was uneventful. The histopathological sections were suggestive of mature ganglioneuroma. She was discharged in stable condition with follow-up at neurosurgery clinic. Conclusion. Giant ganglioneuromas are rare, benign tumors of sympathetic neurons. Complete surgical resection is the most effective therapeutic option for ganglioneuroma to avoid recurrence. Given the benign nature of ganglioneuroma, chemotherapy and radiotherapy tend to have a limited role following surgical resection. [ABSTRACT FROM AUTHOR]
- Abstract:
Copyright of Case Reports in Surgery is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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