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Analyzing the Impact of Concomitant COVID-19 Infection on Outcomes in Trauma Patients.
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- Author(s): Rafaqat, Wardah (AUTHOR); Abiad, May (AUTHOR); Lagazzi, Emanuele (AUTHOR); Argandykov, Dias (AUTHOR); Proaño-Zamudio, Jefferson A. (AUTHOR); Velmahos, George C. (AUTHOR); Hwabejire, John O. (AUTHOR); Parks, Jonathan J. (AUTHOR); Luckhurst, Casey M. (AUTHOR); DeWane, Michael P. (AUTHOR)
- Source:
American Surgeon. Jun2024, Vol. 90 Issue 6, p1599-1607. 9p. - Source:
- Additional Information
- Subject Terms:
- Abstract: Background: The impact of COVID-19 infection at the time of traumatic injury remains understudied. Previous studies demonstrate that the rate of COVID-19 vaccination among trauma patients remains lower than in the general population. This study aims to understand the impact of concomitant COVID-19 infection on outcomes in trauma patients. Methods: We conducted a retrospective cohort study of patients ≥18 years old admitted to a level I trauma center from March 2020 to December 2022. Patients tested for COVID-19 infection using a rapid antigen/PCR test were included. We matched patients using 2:1 propensity accounting for age, gender, race, comorbidities, vaccination status, injury severity score (ISS), type and mechanism of injury, and GCS at arrival. The primary outcome was inpatient mortality. Secondary outcomes included hospital length of stay (LOS), Intensive Care Unit (ICU) LOS, 30-day readmission, and major complications. Results: Of the 4448 patients included, 168 (3.8%) were positive (COV+). Compared with COVID-19-negative (COV-) patients, COV+ patients were similar in age, sex, BMI, ISS, type of injury, and regional AIS. The proportion of White and non-Hispanic patients was higher in COV- patients. Following matching, 154 COV+ and 308 COV- patients were identified. COVID-19-positive patients had a higher rate of mortality (7.8% vs 2.6%; P =.010), major complications (15.6% vs 8.4%; P =.020), and thrombotic complications (3.9% vs.6%; P =.012). Patients also had a longer hospital LOS (median, 9 vs 5 days; P <.001) and ICU LOS (median, 5 vs 3 days; P =.025). Conclusions: Trauma patients with concomitant COVID-19 infection have higher mortality and morbidity in the matched population. Focused interventions aimed at recognizing this high-risk group and preventing COVID-19 infection within it should be undertaken. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of American Surgeon is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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