A blueprint for tumor-infiltrating B cells across human cancers.

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  • Additional Information
    • Subject Terms:
      B cells; B cell differentiation; PLASMA cells
    • Abstract:
      The article offers information on the landscape of tumor-infiltrating B cells across various cancer types, focusing on their abundance, differentiation states, and potential for improving immunotherapy response. Topics include the heterogeneity within B and plasma cells; the identification of B cell subsets and plasma cell subsets; and the impact of metabolic-epigenetic-signaling networks on tumor-infiltrating B cell differentiation.