مطالعه اثر غلظتهای تحت کشنده علف کش پاراکوات بر بافت و شاخصهای )Barbus sharpeyi کلیوی. (Persian)

Study of sublethal concentrations of paraquat herbicide on tissue and kidney factors of Barbus sharpeyi. (English)

According to high solubility and frequent use of paraquat, large amounts of it can penetrate into surface waters through runoff and have destructive effects on living organisms. Therefore, in the present study, the toxic effects of paraquat on the kidney and the its functional factors, including creatinine, urea, and uric acid, were investigated in benny fish (Barbus sharpeyi). 40 benny fish were divided into 4 treatments including 0% (control, t0), 25% (t1), 50% (t2) and 75% (t3) paraquat lethal concentration (0, 0.38, 0.76, and 1.14mg/L, respectively). After 96 hours of exposure, kidney tissue samples were taken for tissue studies and blood serum sampled to check changes in kidney functional factors. Injuries such as shriveling of glomerulus and renal tubules, hyperemia, destruction of tubule epithelium, dilation of urinary space and decrease in the lumen diameter of urinary tubules were seen in exposure to paraquat. Creatinine in groups t2 and t3 and uric acid in t1 showed significant changes compared to the control group (P<0.05). As the concentration increased, paraquat caused more severe and widespread damage in the kidney. The results showed severe destruction of kidney tissue in the group t3, and as a result, creatinine also increased. [ABSTRACT FROM AUTHOR]

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