National Institutes for Food and Drug Control Researchers Have Provided New Study Findings on Collagen Type XVIII (Generation and utilization of endostatin-sensitive cell lines for assessing the biological activity of endostatin).

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  • Source:
    Drug Week; 5/3/2024, p1154-1154, 1p
  • Additional Information
    • Abstract:
      A new study conducted by researchers at the National Institutes for Food and Drug Control has provided findings on collagen type XVIII. The study focused on the biological activity of recombinant proteins, which are increasingly being used to treat human diseases. The researchers used gene-editing technology to identify potential endostatin-resistant genes and successfully constructed a highly sensitive cell line for detecting the biological activity of endostatin. The method was validated and produced consistent results with higher sensitivity and more stable data compared to traditional methods. This research provides a novel solution for assessing the biological activity of recombinant proteins. [Extracted from the article]
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