Profil Pasien Vitiligo di Rumah Sakit Dr. Sitanala Januari 2020 – Juni 2023. (Indonesian)

Vitiligo is a chronic skin disorder characterized by depigmentation or hypopigmentation of the skin and mucosa. The etiology of this disease is unknown, but there are several theories that explain the loss of epidermal melanocytes in vitiligo. The pathophysiology of vitiligo includes autoimmune mechanism, cytotoxic, biochemical, oxidant- antioxidant, neural, and virus. The lesions of vitiligo are macules and depigmented patches with distinct margins. Diagnosis of vitiligo uses histopathological biopsy for cases that are atypical or doubtful. The classifications are segmental vitiligo, acrofacial, generalized, and universal, or by pattern of involvement as focal, mixed, and the mucosa. Laboratory examinations are helpful, including thyroid stimulating hormone level, anti-nuclear antibody, and complete blood count. Histological examination found no melanocytes in the skin lesions. Treatments are topical corticosteroids, topical imunumodulator, PUVA, NBUVB, excimer laser, and surgery. The objective of this study was to determine the profile of vitiligo patients at dr. Sitanala Hospital from the medical record period of January 2020 until Juny 2023.The study design used a descriptive study. The study was conducted at the Dermato Venerology Aesthetic Polyclinic of the dr. Sitanala Hospital from the medical record period of January 2020 until June 2023. Patient of vitiligo the Dermato Venerology Aesthetic Polyclinic of the dr. Sitanala Hospital from the medical record period of January 2020 until Juny 2023 were 123 patients. The most frequent woman as much as 65 patients (52,84%). The most frequent age were >41 years old as much as 29 patients (23,57%). 41 of the patients were students (33,33%). Majority of patients 82,92% had multiple lesions. Location of the lesions on cheeks 37 patients (30,88%). Classifification of the acrofacial lesions 54 patients (43,9%). 61,78% came to out patient clinic after having vitiligo for 1 to 5 years. The average of vitiligo case in dr. Sitanala Hospital is 123 patient and mostly woman and had multiple lesions. [ABSTRACT FROM AUTHOR]

Vitiligo adalah kelainan kulit yang kronis, ditandai dengan bercak depigmentasi atau hipopigmentasi kulit dan mukosa. Penyebab pasti penyakit ini belum diketahui, tetapi terdapat beberapa teori yang menjelaskan tentang hilangnya melanosit epidermal pada vitiligo. Teori patofisiologi vitiligo yang paling berperan antara lain mekanisme autoimun, sitotoksik, biokimia, oksidan-antioksidan, neural, dan virus. Penyakit ini memiliki lesi berupa makula dan patch depigmentasi dengan batas tegas, bentuk dan ukuran bervariasi. Penegakan diagnosis vitiligo memerlukan histopatologi apabila mendapatkan kasus yang tidak khas atau diagnosis yang masih meragukan. Klasifikasi vitiligo antara lain segmental, akrofasial, generalisata, dan universal, atau berdasarkan pola daerah yang terkena yaitu jenis fokal, campuran, dan mukosa. Pemeriksaan laboratorium yang membantu dalam membangun diagnosis vitiligo, antara lain kadar thyroid stimulating hormone, anti-nuclear antibody, dan darah lengkap. Pada pemeriksaan histologi tidak ditemukan melanosit pada lesi kulit. Pengobatan berupa kortikosteroid topikal, imunumodulator topikal, PUVA, NBUVB, laser excimer dan bedah. Mengetahui profil pasien vitiligo di RS Sitanala periode Januari 2020 sampai Juni 2023. Penelitian yang digunakan studi deskriptif retrospektif. Penelitian dilaksanakan di Poliklinik Dermatovenerologi Estetika RS dr. Sitanala dari rekam medis periode Januari 2020 sampai dengan Juni 2023. Pasien vitiligo di Poliklinik Dermatovenerologi Estetika RS dr. Sitanala periode Januari 2020 sampai dengan Juni 2023 adalah 123 pasien. Distribusi terbanyak wanita yaitu 65 pasien (52,84%). Distribusi terbanyak pada kelompok usia > 41 tahun sebanyak 29 pasien (23,57%). 41 pasien (33,33%) merupakan pelajar. Sebagian besar pasien (82,92%) memiliki lesi multipel. Lokasi lesi terbanyak di pipi sebanyak 37 pasien (30,08%), tipe lesi akrofasial sebanyak 54 pasien (43,9%). Sebanyak 61,78% pasien datang berobat setelah menderita vitiligo dengan durasi 1-5 tahun. Kasus vitiligo di RS dr. Sitanala periode Januari 2020- Juni 2023 berjumlah 123 pasien, mayoritas wanita dan lesi multipel. [ABSTRACT FROM AUTHOR]

Copyright of Syntax Idea is the property of Ridwan Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)