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Vitamin D receptor: a highly versatile nuclear receptor.
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- Author(s): Wu-Wong JR;Wu-Wong JR
- Source:
Kidney international [Kidney Int] 2007 Aug; Vol. 72 (3), pp. 237-9.
- Publication Type:
Journal Article; Comment
- Language:
English
- Additional Information
- Source:
Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print Cited Medium: Print ISSN: 0085-2538 (Print) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE
- Publication Information:
Publication: 2016- : New York : Elsevier
Original Publication: New York, Springer-Verlag.
- Subject Terms:
- Abstract:
Vitamin D receptor (VDR) modulators are used to treat hyperparathyroidism secondary to chronic kidney disease (CKD). The therapy is associated with reduced mortality in stage 5 CKD patients, who experience an extremely high cardiovascular disease (CVD)-related mortality rate. Chen et al. report that VDR is involved in regulating type A natriuretic peptide receptor (NPR-A) in inner medullary collecting duct cells. The regulation of NPR-A may be one of several mechanisms by which VDR activation reduces CVD risk in CKD.
- Comments:
Comment on: Kidney Int. 2007 Aug;72(3):300-6. (PMID: 17440494)
- Accession Number:
0 (Receptors, Calcitriol)
0 (Receptors, Cytoplasmic and Nuclear)
EC 1.14.15.18 (25-Hydroxyvitamin D3 1-alpha-Hydroxylase)
EC 4.6.1.2 (Guanylate Cyclase)
EC 4.6.1.2 (Receptors, Atrial Natriuretic Factor)
EC 4.6.1.2 (atrial natriuretic factor receptor A)
- Publication Date:
Date Created: 20070727 Date Completed: 20070925 Latest Revision: 20191210
- Publication Date:
20221213
- Accession Number:
10.1038/sj.ki.5002428
- Accession Number:
17653231
No Comments.