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Findings from School of Pharmacy Provides New Data on Nanoparticles (Galactosyl Bodipy-based Nanoparticles As a Type-i Photosensitizer for Hepg2 Cell Targeted Photodynamic Therapy).
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- Abstract:
A study conducted in Weifang, People's Republic of China, has developed galactosyl diiodo-BODIPY-based nanoparticles as a type-I photosensitizer for targeted photodynamic therapy of HepG2 cells. The nanoparticles were found to have high water solubility and excellent chemo- and photo-stability. The galactosyl-modified nanoparticles were able to target and concentrate on HepG2 cells, triggering cell death under specific light irradiation. This research provides a promising strategy for the construction of glycoside-recognized type-I photosensitizers for tumor cell imaging and photodynamic therapy. [Extracted from the article]
- Abstract:
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