Synthesis, Characterization, Enhanced Solubility and Antioxidant Activity of the Inclusion Compound of 2-Amino-N-o-tolyl-benzamide and Beta Cyclodextrin.

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    • Abstract:
      Summary: The objectives of this research, were to study the effect of beta cyclodextrin on the enhancement of the solubility and the antioxidant activity of 2-Amino-N-o-tolyl-benzamide (ATB). ATB was obtained by a new synthesis method and used to form inclusion compound macromolecule with β-CD. The characterization of the ATB and the complex were subsequently established by FT-IR; 1H NMR; 13C NMR; NMR 2D spectra and XRD. The optical activity was measured. The interaction of β-CD and ATB was also analyzed by UV-Vis spectroscopy in order to determine the formation constant. The stoichiometry of the complex was 1:1. Furthermore, the solubility and antioxidant activity of ATB were significantly enhanced upon complexation with β CD. [ABSTRACT FROM AUTHOR]
    • Abstract:
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