Researchers at Army Medical University Release New Data on Spinal Surgery (Dynamics of N6-methyladenosine Modification During Aging and Their Potential Roles In the Degeneration of Intervertebral Disc).

Researchers at Army Medical University in Chongqing, China have conducted a study on the dynamics of N6-methyladenosine (m6A) modification during the aging of intervertebral discs (IVD). The study aimed to explore the distribution and pattern of m6A modification in the nucleus pulpous (NP) tissues of rats at different ages. The researchers found significant changes in the global m6A level and the expression of certain genes in NP tissues from older rats compared to younger rats. The study suggests that these findings may provide new insights into the mechanisms and therapies of intervertebral disc degeneration (IDD) from the perspective of aging. [Extracted from the article]

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