Severe liver degeneration in mice lacking the IkappaB kinase 2 gene.

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  • Additional Information
    • Subject Terms:
      PROTEIN kinases; LIVER diseases
    • Abstract:
      Focuses on liver degeneration in mice lacking the inhibitor of kappa B kinase 2 gene. Role of the transcription factor NF-kappaB; Inactivation of the gene encoding IKK2; Signal-induced IkappaB phosphorylation and degradation.