ΜΕΛΑΝΩΜΑ ΣΤΟΜΑΤΙΚΟΥ ΒΛΕΝΝΟΓΟΝΟΥ: ΠΑΡΟΥΣΙΑΣΗ ΠΕΡΙΠΤΩΣΗΣ ΠΟΥ ΜΙΜΕΙΤΑΙ ΚΛΙΝΙΚΑ ΚΑΛΟΗΘΗ ΒΛΑΒΗ ΚΑΙ ΒΙΒΛΙΟΓΡΑΦΙΚΗ ΑΝΑΣΚΟΠΗΣΗ. (Greek, Ancient (to 1453))

ORAL MUCOSAL MELANOMA: REPORT OF A CASE CLINICALLY MIMICKING A BENIGN LESION AND LITERATURE REVIEW. (English)

Melanoma is a malignant neoplasm that rarely affects the oral mucosa. At early stages of development, it might manifest as a melanotic macule or a nodule, usually involving the hard palate and the upper gingiva. Herein, a case of a patient presenting with a melanotic macule on hard palate and a melanotic nodule on the soft palate is presented. The lesions clinically resembled an oral melanotic macule and a nevus, respectively, but the microscopic examination revealed that the macule showed features of melanocytic hyperplasia, while the nodule was finally diagnosed as melanoma. The diagnosis of melanoma is rendered by histopathological examination and is confirmed by immunohistochemical analysis. Data regarding its etiopathogeneses are scarce and are mainly derived from epidemiological studies. Despite advances in treatment modalities, its prognosis remains poor. The dentist should be aware that oral mucosal melanoma at initial stages might mimic benign pigmented lesions. Therefore, in case of any solitary pigmented lesion, in which the diagnosis cannot be established with certainty based on clinical or radiographic findings, biopsy is recommended to rule out melanoma. [ABSTRACT FROM AUTHOR]

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