Studies in the Area of HIV/AIDS Reported from Icahn School of Medicine at Mount Sinai (Innate Immune Responses Reverse Hiv Cognitive Disease In Mice: Profile By Rnaseq In the Brain).

A recent report discusses research conducted at the Icahn School of Medicine at Mount Sinai on the topic of HIV/AIDS. The study focused on the effects of HIV infection on the brain and the potential for reversal of cognitive impairment using a specific treatment. The researchers infected mice with a chimeric form of HIV and observed changes in brain gene expression. They found that treatment with polyinosinic-polycytidylic acid (poly I:C) reversed cognitive impairment and reduced virus burden in the mice. The study highlights the potential for innate immune responses to block HIV infection and associated brain dysfunction. [Extracted from the article]

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