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Laser ablation on vascular diseases: mechanisms and influencing factors.
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- Author(s): Zhang, Chenghong1 (AUTHOR); Lyu, Wenhao1 (AUTHOR); Qiu, Pengtianyu1 (AUTHOR); Zhang, Congyu1 (AUTHOR); Zhao, Xiaoli1 (AUTHOR); Wang, Xiaogang2 (AUTHOR); He, Boqu2 (AUTHOR); Fu, Bo1,2 (AUTHOR) ; Ji, Xunming3 (AUTHOR)
- Source:
Lasers in Medical Science. 12/29/2023, Vol. 39 Issue 1, p1-8. 8p.
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- Additional Information
- Abstract:
Vascular diseases, such as venous insufficiency and coronary artery diseases, have been threatening the health of people. Efficient treatment with proper postoperative care is required to relieve the pain of the patients. Traditionally, venous insufficiency is treated with ligation and stripping, an open surgery whose complication rate cannot be ignored. Coronary artery disease is often treated with balloon angioplasty during which undilatable lesions may be encountered, limiting the efficacy of this approach. With advances in laser photonics and percutaneous coronary intervention procedure, laser ablation is emerging as an alternative and adjunctive therapy for these diseases. Endovenous laser ablation has the advantages of high success rate, low complication risk, and fast postoperative recovery. Laser ablation in arteries can handle uncrossable or undilatable lesions with a low incidence of serious complications. In this review, previously published research concerning vascular diseases and their therapies are analyzed in order to provide a clear explanation of the mechanisms and merits of laser ablation. For endovenous laser ablation, the main mechanisms are steam bubbles, heat conduction, and heat pipe, and three main influencing factors are wavelength, fiber types, and laser energy density. For excimer laser coronary atherectomy, the main mechanisms are photochemical, photothermal, and photomechanical effects, and three main influencing factors are catheter, medium, and laser parameters. [ABSTRACT FROM AUTHOR]
- Abstract:
Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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