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Folly Beach Library
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Edgar Allan Poe/Sullivan's Island Library
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Wando Mount Pleasant Library
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Village Library
9 a.m. – 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
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Otranto Road Library
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McClellanville Library
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Hurd/St. Andrews Library
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Quinoa (Chenopodium quinoa Willd.) supplemented cafeteria diet ameliorates glucose intolerance in rats.
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- Author(s): Ozcaliskan Ilkay, Hatice1,2 (AUTHOR); Karabulut, Derya3 (AUTHOR); Kamaci Ozocak, Gonca4 (AUTHOR); Mehmetbeyoglu, Ecmel5 (AUTHOR); Kaymak, Emin6 (AUTHOR); Kisioglu, Betul1 (AUTHOR); Cicek, Betul2 (AUTHOR); Akyol, Asli1 (AUTHOR)
- Source:
Food Science & Nutrition. Nov2023, Vol. 11 Issue 11, p6920-6930. 11p.- Subject Terms:
- Source:
- Additional Information
- Abstract: Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with rich nutritional composition, gluten free, and organoleptic. The primary aim of this study was to elucidate the possible protective roles of quinoa in glucose homeostasis in a model of cafeteria diet‐induced obesity. Male Wistar rats (3 weeks of age) were randomly allocated to be fed by; control chow (CON; n = 6), quinoa (QUI; n = 6), cafeteria (CAF; n = 6), or quinoa and cafeteria (CAFQ; n = 6) for 15 weeks. CAFQ resulted in decreased saturated fat, sugar, and sodium intake in comparison with CAF. Compared to CON, CAF increased body weight gain, plasma insulin, plasma glucose, decreased liver IRS‐1, AMPK mRNA expressions, and pancreatic β‐cell insulin immunoreactivity, and developed hepatocyte degeneration and microvesicular steatosis. Compared to CAF, QUI lowered body weight, plasma glucose, and plasma insulin, increased liver IRS‐1 and AMPK mRNA expressions, and pancreatic β‐cell insulin immunoreactivity. Compared to CAF, CAFQ lowered plasma glucose, increased liver IRS‐1 mRNA expressions, increased pancreatic β‐cell insulin immunoreactivity, and lowered hepatocyte degeneration and microvesicular steatosis. Dietary treatments did not influence IRS‐2, AKT2, and INSR mRNA expressions. HOMA‐IR, HOMA‐β, and QUICKI were also similar between groups. Restoration of insulin in CAFQ islets was as well as that of CON and QUI groups. In conclusion, as a functional food, quinoa may be useful in the prevention of obesity and associated metabolic outcomes such as glucose intolerance, disrupted pancreatic β‐cell function, hepatic insulin resistance, and lipid accumulation. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Food Science & Nutrition is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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