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Antifertility activity of the methanolic leaf extract of Cissampelos pareira in female albino mice.
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- Author(s): Ganguly M;Ganguly M; Kr Borthakur M; Devi N; Mahanta R
- Source:
Journal of ethnopharmacology [J Ethnopharmacol] 2007 May 22; Vol. 111 (3), pp. 688-91. Date of Electronic Publication: 2007 Jan 26.
- Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
- Language:
English
- Additional Information
- Source:
Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0378-8741 (Print) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
- Publication Information:
Publication: Limerick : Elsevier Sequoia
Original Publication: Lausanne, Elsevier Sequoia.
- Subject Terms:
- Abstract:
meenakshi Cissampelos pareira Linn. is one of the folk medicinal plants commonly used as antifertility agent in some places of India. The aim of the present study was to evaluate the validity of the antifertility effect of the leaf extract. Cissampelos pareira leaf extract, when administered orally, altered the estrous cycle pattern in female mice, prolonged the length of estrous cycle with significant increase in the duration of diestrus stage and reduced significantly the number of litters in albino mice. The analysis of the principal hormones involved in estrous cycle regulation showed that the plant extract altered gonadotropin release (LH, FSH and prolactin) and estradiol secretion. The results indicated the antifertility effect of Cissampelos pareira leaf extract in female albino mice. The oral LD50 of the extract was found to be 7.3 g/kg in mice.
- Accession Number:
0 (Contraceptive Agents, Female)
0 (Plant Extracts)
4TI98Z838E (Estradiol)
9002-62-4 (Prolactin)
9002-67-9 (Luteinizing Hormone)
9002-68-0 (Follicle Stimulating Hormone)
- Publication Date:
Date Created: 20070228 Date Completed: 20070726 Latest Revision: 20181201
- Publication Date:
20240829
- Accession Number:
10.1016/j.jep.2007.01.023
- Accession Number:
17324540
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