Carbapenemase‐producing Enterobacterales: a profound threat to Australian public health.

(Box 1). 1 BOX Actions to enhance effective carbapenemase-producing Enterobacterales (CPE) surveillanc... Nationally consistent notification of CPE, incorporating case definitions for colonisation and infection, across all states and territories. Currently, CPE infection is only notifiable in five of the eight states and territories, and consequently, CPE burden is likely underestimated. Of those carrying CPE, it is estimated that 10-30% will develop a CPE infection.[4] The first such infection to be described was an I Enterobacter cloacae i isolate from a patient treated for a subcutaneous abscess in a French hospital in 1990.[5] Since then, the rapid spread of CPE has been clearly evident. Keywords: Prevention and control; Public health; Anti-infective agents; Drug resistance; microbial; Microbiology EN Prevention and control Public health Anti-infective agents Drug resistance microbial Microbiology 290 292 3 10/04/23 20231001 NES 231001 The spread of carbapenemase-producing Enterobacterales (CPE) is a major threat to health care systems worldwide.[1] In regions where CPE has become endemic, its impact on health outcomes has been catastrophic. [Extracted from the article]

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