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Illuminating cardiac development: Advances in imaging add new dimensions to the utility of zebrafish genetics.
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- Author(s): Schoenebeck JJ;Schoenebeck JJ; Yelon D
- Source:
Seminars in cell & developmental biology [Semin Cell Dev Biol] 2007 Feb; Vol. 18 (1), pp. 27-35. Date of Electronic Publication: 2006 Dec 27.
- Publication Type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
- Language:
English
- Additional Information
- Source:
Publisher: Academic Press Country of Publication: England NLM ID: 9607332 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1084-9521 (Print) Linking ISSN: 10849521 NLM ISO Abbreviation: Semin Cell Dev Biol Subsets: MEDLINE
- Publication Information:
Publication: London : Academic Press
Original Publication: London, UK : Academic Press, c1996-
- Subject Terms:
- Abstract:
The use of the zebrafish as a model organism for the analysis of cardiac development is no longer proof-of-principle science. Over the last decade, the identification of a variety of zebrafish mutations and the subsequent cloning of mutated genes have revealed many critical regulators of cardiogenesis. More recently, increasingly sophisticated techniques for phenotypic characterization have facilitated analysis of the specific mechanisms by which key genes drive cardiac specification, morphogenesis, and function. Future enrichment of the arsenal of experimental strategies available for zebrafish should continue the yield of high returns from such a small source.
- Number of References:
60
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- Grant Information:
R01 HL069594 United States HL NHLBI NIH HHS; R01 HL081911 United States HL NHLBI NIH HHS
- Publication Date:
Date Created: 20070124 Date Completed: 20070518 Latest Revision: 20181113
- Publication Date:
20240829
- Accession Number:
PMC1876688
- Accession Number:
10.1016/j.semcdb.2006.12.010
- Accession Number:
17241801
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