[Comparative characteristic of Mycobacterium tuberculosis strain drug sensitivity].

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  • Author(s): Kondratiuk NV; Sybirnyĭ AV; Sybirna RI
  • Source:
    Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) [Mikrobiol Z] 2006 Jul-Aug; Vol. 68 (4), pp. 54-9.
  • Publication Type:
    Comparative Study; English Abstract; Journal Article
  • Language:
    Ukrainian
  • Additional Information
    • Source:
      Publisher: Naukova Dumka Country of Publication: Ukraine NLM ID: 9318954 Publication Model: Print Cited Medium: Print ISSN: 1028-0987 (Print) Linking ISSN: 10280987 NLM ISO Abbreviation: Mikrobiol Z Subsets: MEDLINE
    • Publication Information:
      Original Publication: Kyïv : Naukova Dumka, c1993-
    • Subject Terms:
      Mycobacterium tuberculosis*/drug effects ; Mycobacterium tuberculosis*/growth & development ; Mycobacterium tuberculosis*/isolation & purification; Antitubercular Agents/*pharmacology; Bacterial Typing Techniques ; Humans ; Microbial Sensitivity Tests ; Tuberculosis, Osteoarticular/microbiology ; Tuberculosis, Pulmonary/microbiology
    • Abstract:
      The medicinal sensitivity of tuberculosis mycobacteria strains of the patients with pulmonary and extrapulmonary tuberculosis was studied in completely automated system Bactec MGIT. A comparison was also made with the research results of medicinal sensitivity by the method of absolute concentrations on Levenstein-Jensen hard nutrient medium. A considerable coincidence in results of these two methods: a percentag of analogous results of the test of sensitivity of MBT to ABS in Bactec MGIT 960 system and by the method of absolute concentrations for riphampicyn and izoniazyde was 97.2%, for streptomycin - 94.4%. Besides, the term of obtaining the results in Bactec MGIT 960 automated system is 5 to 13 days, while with the absolute concentrations method the term of obtaining the results is 21 to 26 days. This plays an important role in prescribing the proper antituberculous therapy scheme.
    • Accession Number:
      0 (Antitubercular Agents)
    • Publication Date:
      Date Created: 20061115 Date Completed: 20061213 Latest Revision: 20061114
    • Publication Date:
      20231215
    • Accession Number:
      17100329