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Derivation of mouse sarcoma virus (Kirsten) by acquisition of genes from heterologous host.
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- Author(s): Roy-Burman P; Klement V
- Source:
The Journal of general virology [J Gen Virol] 1975 Aug; Vol. 28 (2), pp. 193-8.
- Publication Type:
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
- Language:
English
- Additional Information
- Source:
Publisher: Microbiology Society Country of Publication: England NLM ID: 0077340 Publication Model: Print Cited Medium: Print ISSN: 0022-1317 (Print) Linking ISSN: 00221317 NLM ISO Abbreviation: J Gen Virol Subsets: MEDLINE
- Publication Information:
Publication: 2015- : London : Microbiology Society
Original Publication: London, Cambridge Univ. Press for the Society for General Microbiology.
- Subject Terms:
- Abstract:
The technique of virus RNA-cellular DNA hybridization in solution with DNA excess was used to compared the nucleotide sequences of the 70 S RNA genome of the Kirsten mouse sarcoma virus (Ki-MSV) with that of mouse erythroblastosis virus (MEV) which gave rise to Ki-MSV after in vivo propagation in rat. It is suggested that a loss of about 30% of the genomic sequences of MEV with a concomitant gain of roughly equal amounts of rat-specific sequences in a genetically stable recombinant state led to the formation of Ki-MSV.
- Accession Number:
0 (DNA, Neoplasm)
0 (Nucleotides)
0 (RNA, Viral)
9007-49-2 (DNA)
- Publication Date:
Date Created: 19750801 Date Completed: 19760102 Latest Revision: 20061115
- Publication Date:
20250114
- Accession Number:
10.1099/0022-1317-28-2-193
- Accession Number:
170369
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