Cell Cycle Inhibitory Activity of 137 Traditional Chinese Herbal Medicines Against tsFT210 Cell Line.

One hundred thirty-seven species of traditional Chinese herbal medicines belonging to 61 families were collected from Yunnan and Sichuan province in the People's Republic of China and tested for cell cycle inhibitory activity against tsFT210 cell line. Thirty-one traditional Chinese medicines from 18 families showed bioactivity, and the ethanol extract of Rubus aleaefolius Poir. rhizome and Trewia nudiflora L. rhizome exhibited the strongest inhibitory activity on cell cycle progression at the G 0 /G 1 and G 2 /M phases, respectively. The screening results indicated that this bioassay is suitable for screening bioactive natural products from herbal medicines. [ABSTRACT FROM AUTHOR]

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