Nocturnal overdistension may cause bladder deterioration.

The article reports that nocturnal overdistension of the bladder can cause bladder deterioration in children with neurogenic bladder. However, the condition is amenable to treatment by nighttime bladder emptying. It is reported that the strategy of nocturnal bladder emptying led to improvement or resolution in bladder deterioration in 14 of 18 children studies, as well as improvement or complete resolution of symptoms in a majority of patients with hydronephrosis, recurrent urinary tract infection, and incontinence.