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9 a.m. - 6 p.m.
Phone: (843) 722-7550
West Ashley Library
9 a.m. - 6 p.m.
Phone: (843) 766-6635
Folly Beach Library
9 a.m. - 1 p.m.
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Wando Mount Pleasant Library
9 a.m. - 6 p.m.
Phone: (843) 805-6888
Village Library
9 a.m. - 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. - 6 p.m.
Phone: (843) 889-3300
Otranto Road Library
9 a.m. - 6 p.m.
Phone: (843) 572-4094
Mt. Pleasant Library
9 a.m. – 6 p.m.
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McClellanville Library
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Keith Summey North Charleston Library
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John's Island Library
9 a.m. - 6 p.m.
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Hurd/St. Andrews Library
9 a.m. - 6 p.m.
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Phone: (843) 552-6466
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9 a.m. - 6 p.m.
Phone: (843) 795-6679
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9 a.m. - 6 p.m.
Phone: (843) 805-6930
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Phone: (843) 805-6892
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Phone: (843) 805-6909
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Effects of Early Chemoprophylaxis in Traumatic Brain Injury and Risk of Venous Thromboembolism.
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- Author(s): Shulkosky, Megan M.; Han, Emily J.; Wahl, Wendy L.; Hecht, Jason P.
- Source:
American Surgeon. Jun2023, Vol. 89 Issue 6, p2513-2519. 7p. - Source:
- Additional Information
- Subject Terms:
- Abstract: Background: The optimal timing to initiate venous thromboembolism (VTE) prophylaxis in patients with a traumatic brain injury (TBI) is still unknown. We designed a study to determine the effect that timing of initiation of VTE prophylaxis has on VTE rates in TBI patients. Methods: Patient records were obtained from 32 level 1 and 2 trauma centers in the Michigan Trauma Quality Improvement Program from 2008 to 2018. Overall, 5589 patients with a TBI were included and split into cohorts based on VTE prophylaxis initiation time. Outcomes included rate of VTE, mortality, and serious in-hospital complications. Results: There were nine patients (1.3%) in the <24 hour group with a VTE as compared to 36 (2.6%) in the 24-48 hour group, 51 (4.1%) in the 48-72 hour group, and 181 (8.1%) in the >72 hour group (P <.001). The adjusted odds of VTE were significantly greater in patients initiated within 48-72 hours (AOR 2.861, 95% CI 1.271-6.439) and >72 hours (AOR 3.963, 95% CI 1.824-8.612) compared to <24 hours. Patients that received VTE prophylaxis within 24 hours had similar rates of serious in-hospital complication as patients initiated within 24-48 hours (AOR.956, 95% CI.637-1.434) and 48-72 hour (AOR 1.132, 95% CI.757-1.692) but less than the >72 hour group (AOR 1.662, 95% CI 1.154-2.393) groups. Discussion: Patients initiated on VTE prophylaxis within 48 hours of presentation had lower incidence of VTE without a significant increase in serious complications. [ABSTRACT FROM AUTHOR]
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