MGOUN3: evidence for chromatin-mediated regulation of FLC expression.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Oxford University Press Country of Publication: England NLM ID: 9882906 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-0957 (Print) Linking ISSN: 00220957 NLM ISO Abbreviation: J Exp Bot Subsets: MEDLINE
    • Publication Information:
      Original Publication: Oxford, UK : Oxford University Press,
    • Subject Terms:
      Arabidopsis/*physiology ; Arabidopsis Proteins/*metabolism ; Arabidopsis Proteins/*physiology ; Chromatin/*metabolism ; Flowers/*growth & development ; MADS Domain Proteins/*metabolism; Arabidopsis/genetics ; Chromatin/physiology ; Gene Expression ; Genes, Plant ; Meristem ; Mutation ; Phenotype ; Photoperiod ; Plant Leaves/metabolism ; Time Factors
    • Abstract:
      The MGOUN3(MGO3)/BRUSHY1(BRU1)/TONSOKU(TSK) gene of Arabidopsis thaliana encodes a nuclear leucine-glycine-asparagine (LGN) domain protein that may be implicated in chromatin dynamics and genome maintenance. Mutants with defects in MGO3 display a fasciated stem and disorganized meristem structures. The transition to flowering was examined in mgo3 mutants and it was found that, under short days, the mutants flowered significantly earlier than the wild-type plants. Study of flowering-time associated gene expression showed that the floral transition inhibitor gene FLC was under-expressed in the mutant background. Ectopic expression of the flower-specific genes AGAMOUS (AG), PISTILLATA (PI), and SEPALLATA3 (SEP3) in mgo3 vegetative organs was also detected. Western blot and chromatin immunoprecipitation experiments suggested that histone H3 acetylation may be altered in the mgo3 background. Together, these data suggest that MGO3 is required for the correct transition to flowering and that this may be mediated by histone acetylation and associated changes in FLC expression.
    • Accession Number:
      0 (Arabidopsis Proteins)
      0 (Chromatin)
      0 (FLF protein, Arabidopsis)
      0 (MADS Domain Proteins)
      0 (MGOUN3 protein, Arabidopsis)
    • Publication Date:
      Date Created: 20060527 Date Completed: 20061017 Latest Revision: 20060629
    • Publication Date:
      20240829
    • Accession Number:
      10.1093/jxb/erj169
    • Accession Number:
      16728410