[Persistence of the control of the fluctuations of heart rate in the anesthetized and pithed adult rat. Effect of enteraminergic drugs].

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  • Author(s): Bernardi M;Bernardi M; Di Sarra B; Montecchiani G; Re L; Rossini L; Tonnini C
  • Source:
    Bollettino della Societa italiana di biologia sperimentale [Boll Soc Ital Biol Sper] 1991 Jan; Vol. 67 (1), pp. 47-54.
  • Publication Type:
    Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • Language:
    Italian
  • Additional Information
    • Transliterated Title:
      Persistenza del controllo delle fluttuazioni della frequenza cardiaca nel ratto adulto, anestetizzato e "periferico". Effetti di trattamenti farmacologici enteraminergici.
    • Source:
      Publisher: PAGEPress Country of Publication: Italy NLM ID: 7506962 Publication Model: Print Cited Medium: Print ISSN: 0037-8771 (Print) Linking ISSN: 00378771 NLM ISO Abbreviation: Boll Soc Ital Biol Sper Subsets: MEDLINE
    • Publication Information:
      Publication: 2014- : Pavia, Italy : PAGEPress
      Original Publication: Napoli, Società italiana di biologia sperimentale.
    • Subject Terms:
      Anesthesia*; Decerebrate State/*physiopathology ; Heart Rate/*drug effects ; Indazoles/*pharmacology ; Piperidines/*pharmacology ; Serotonin Antagonists/*pharmacology; Animals ; Depression, Chemical ; Dose-Response Relationship, Drug ; Ether ; Female ; Granisetron ; Male ; Rats ; Ritanserin
    • Abstract:
      Spontaneous fluctuations in heart rate were analyzed by spectral analysis in the ether anesthetized and pithed adult rat. In order to investigate the changes in the spectral pattern of the fluctuations, the selective 5HT-2 and -3 isoreceptor blockers ritanserin and BRL 43694A were used. In both the experimental conditions, ritanserin blockade led to dose-dependent increased fluctuations in HR low and high frequencies. In both the anesthetized and pithed rats, the low frequency range HR fluctuations were drastically reduced by BRL 43694A.
    • Accession Number:
      0 (Indazoles)
      0 (Piperidines)
      0 (Serotonin Antagonists)
      0F5N573A2Y (Ether)
      145TFV465S (Ritanserin)
      WZG3J2MCOL (Granisetron)
    • Publication Date:
      Date Created: 19910101 Date Completed: 19911016 Latest Revision: 20131121
    • Publication Date:
      20221213
    • Accession Number:
      1653577