Atypical Systemic Neonatal Herpes Diagnosed Incidentally in Twin Infants.

ERYTHEMA; ACYCLOVIR; INTRAVENOUS therapy; HERPES simplex; TWINS; MEDICAL screening; OPHTHALMIC drugs; TREATMENT effectiveness; EYE infections; LUMBAR puncture; CESAREAN section; BACTERIAL diseases; POLYMERASE chain reaction; KERATITIS; CHILDREN

Neonatal herpes simplex virus (HSV) infections are serious infections that usually occur in the first few weeks of life. Infants generally present with mucocu-taneous lesions, central nervous system infection, and/or systemic disease. In this case report, we describe a set of twins that had unexpected presentations of neonatal HSV. Twin A was diagnosed incidentally on routine eye exam, and Twin B was diagnosed only because his twin was found to be infected; both infants were still hospitalized and were beyond 1 month of age. These twins exhibited atypical manifestations that diverge from the 3 main categories of neonatal HSV and expand our understanding of the spectrum of disease. [ABSTRACT FROM AUTHOR]

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