"Methods Of Using A Bispecific Antibody That Recognizes Coagulation Factor Ix And/Or Activated Coagulation Factor Ix And Coagulation Factor X And/Or Activated Coagulation Factor X" in Patent Application Approval Process (USPTO 20230159658).

A method for treating and/or reducing the incidence of a disease that develops and/or progresses due to a decrease or deficiency in the activity of blood coagulation factor VIII and/or activated blood coagulation factor VIII (FVIIIa), the method comprising: administering to a subject a bispecific antibody that recognizes (a) blood coagulation factor IX and/or activated blood coagulation factor IX and (b) blood coagulation factor X and/or activated blood coagulation factor X at a weekly loading dose of 3 mg/kg or 4.5 mg/kg of the antibody for one or more weeks or at an every-two-week loading dose of 6 mg/kg of the antibody for two or more weeks; and, after the loading dose administration(s) are complete, administering a maintenance dose of the antibody to the subject one or more times, the maintenance dose being 6 mg/kg of the antibody. [Extracted from the article]

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