Correlation between grading methods of the cochlear endolymphatic hydrops and hearing loss in meniere's disease using three-dimensional real inversion recovery sequences.

RESEARCH; STATISTICS; ACOUSTIC nerve; CONVALESCENCE; MAGNETIC resonance imaging; COMPARATIVE studies; MENIERE'S disease; HEARING disorders; BODY movement; FOOT; RESEARCH funding; STATISTICAL correlation; DISEASE complications

The grading of intracochlear endolymphatic hydrops (EH) in Meniere's disease (MD) varies and lacks uniformity. To compare the grading consistency and correlation between different grade methods of intracochlear EH and hearing loss. Thirty-one patients diagnosed with MD underwent gadolinium-enhanced magnetic resonance imaging. Two radiologists graded the cochlea EH according to M1, M2, M3, or M4. We analysed the grading consistency and correlation between the EH degrees and hearing loss. The weighted kappa coefficients for inter-observer and intra-observer agreements for grading using M1 were good, whereas those for M2, M3, and M4 are excellent (all p < 0.001). The cochlear EH degree based on M2 was correlated with the low-to-mid frequencies, high frequencies, full frequencies, and MD clinical stage (all p < 0.05). The degrees based on M1, M3, M4 were only relevant to some of the 4 items. The grading consistency of M2, M3, M4 is relatively higher than that of M1, and M2 shows the strongest correlation with hearing loss. Our results provide a more accurate method for assessing the clinical severity of MD. [ABSTRACT FROM AUTHOR]

背景：梅尼埃病 (MD) 耳蜗内淋巴积水 (EH) 的分级方法有多种多样, 缺乏统一性。 目的：比较耳蜗内淋巴积水和听力损失的不同分级方法之间的分级一致性和相关性。 材料和方法：31 名诊断为 MD 的患者接受了钆强化磁共振成像。 两位放射科医生根据 M1、M2、M3、或 M4进行了耳蜗EH分级。 我们分析了 EH 程度和听力损失之间的分级一致性和相关性。 结果：在观察者间和观察者内对使用 M1 分级的一致性的加权卡帕系数良好, 而使用 M2、M3 和 M4 的分级的加权卡帕系数极佳（ p都是<0.001）。 基于 M2 的耳蜗 EH 程度与低到中频率、高频、全频率和 MD 临床分期相关（ p都是<0.05）。 基于M1、M3、M4的EH 程度只与 这4 点中的一部分相关。 结论：M2、M3、M4的分极一致性相对高于M1, 且M2 显示出与听力损失的最强相关性。 意义：我们的结果为评估 MD 的临床严重程度提供了一个更准确的方法。 [ABSTRACT FROM AUTHOR]

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