Patent Issued for Anti-STEAP2 antibodies, antibody-drug conjugates, and bispecific antigen-binding molecules that bind STEAP2 and CD3, and uses thereof (USPTO 11633501).

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    • Abstract:
      An isolated antibody or antigen-binding fragment thereof that binds human six-transmembrane epithelial antigen of prostate 2 (STEAP2), wherein the antibody or antigen-binding fragment comprises complementarity determining regions contained within a heavy chain variable region and light chain variable region amino acid sequence pair selected from the group consisting of SEQ ID NOs: 2/10; 18/26; 34/42; 50/58; 66/58; 74/58; 82/58; 90/58; 98/58; 106/114; 122/130; 138/146; 154/162; 170/178; 186/194; 202/210; 218/226; 234/242; 250/258; 266/274; 282/290; 298/306; 314/322; 330/338; 346/354; 362/370; and 378/386. [Extracted from the article]
    • Abstract:
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