Evaluate the in vitro compatibility of a fabricated PCL: Cs blends, and PCL scaffolds.

The structure and biological activity of native extracellular matrix proteins should be reproduced in a tissue engineering scaffold. Electrospinning is a simple and adaptable approach for fabricating ultrathin tissue engineering fibers. Polycaprolactone (PCL) and chitosan nanofibers were electrospun, and the resulting fibers were tested and evaluated by Contact angle test, field emission scanning electron microscopy (FE-SEM), and Fourier transform infrared spectroscopy (FTIR). The tensile strength of fibers was found to be acceptable. In this work the nanofibrous scaffold promoted the growth and proliferation of normal human fibroblast (NHF), with normal morphology, thus demonstrating its suitability as a scaffold for skin regeneration. [ABSTRACT FROM AUTHOR]

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