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دگزمدتومیدین در کنار لیدوکائین در بلوک سوپراکالویکوالر در اعمال جراحی شکستگی اندام فوقانی: کارآزمایی بالینی شاهددار تصادفی.
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- Author(s): بهرام نادری نبی1; عباس صدیقینژاد1; مهران سلیمانها2; سمانه غضنفر طهرا1; زهرا عطرکار روشن3; احمدرضا میربلوک4; محمدرضا حبیبی1; محمد حقیقی1
- Source:
Journal of Guilan University of Medical Sciences. Spring2023, Vol. 32 Issue 1, p66-78. 13p.- Subject Terms:
*LIDOCAINE; *DRUG efficacy; *SURGICAL therapeutics; *HAND injuries; *PAIN measurement; *ORTHOPEDIC surgery; *NERVE block; *ARM; *IMIDAZOLES; *RANDOMIZED controlled trials; *TREATMENT effectiveness; *COMPARATIVE studies; *BLIND experiment; *DESCRIPTIVE statistics; *RESEARCH funding; *STATISTICAL sampling; *HEMODYNAMICS; *DATA analysis software; *BONE fractures; *PHYSIOLOGIC salines; *PHARMACODYNAMICS - Source:
- Additional Information
- Alternate Title: Effect of Adding Dexmedetomidine to Lidocaine in the Supraclavicular Block Technique in Patients Candidate for Upper Extremity Surgery: A Randomized Controlled Clinical Trial.
- Abstract: Background Various drugs are used as adjuvants to improve the quality of supraclavicular block method. Objective This study aims to investigate the effect of adding dexmedetomidine to lidocaine in the supraclavicular block method in patients candidate for upper extremity surgery. Methods This double-blind randomized controlled clinical trial was conducted on 61 patients candidate for upper extremity fracture surgery receiving the supraclavicular block method from 2017 to 2018. They were randomly divided into two groups of lidocaine-normal saline (30 mL of 1.5% lidocaine plus normal saline) and lidocaine-dexmedetomidine (30 mL of 1.5% lidocaine plus 1 μg/kg of dexmedetomidine). The supraclavicular block characteristics and intraoperative hemodynamic changes were measured. Results There was no statistically significant difference between the two groups regarding the demographic factors. The mean age of patients was 43.09±10.92 years, and most of them were male. The mean onset time of sensory-motor blockade was faster and the duration of sensory-motor blockade and analgesia were longer in the lidocaine-dexmedetomidine group than in the other group. These differences were statistically significant. There was significant differences in hemodynamic parameters among nine assessment times in each group and between the two groups. Conclusion Adding dexmedetomidine to lidocaine in the supraclavicular block method accelerates the blockade onset and increases the duration of blockade and analgesia after surgery without causing any considerable side effects. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of Guilan University of Medical Sciences is the property of Journal of Guilan University of Medical Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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