Studies from Guangxi Medical University Add New Findings in the Area of Genomics and Genetics (Circ_0000595 Knockdown Alleviates Cocl2-mediated Effects In Vsmcs By Regulating the Mir-582-3p/adam10 Axis).

According to the news reporters, the research concluded: "Our data verified that circ 0000595 silencing might attenuate CoCl2-mediated impacts in VSMCs by regulating the miR-582-3p/ADAM10 axis, providing new potential roads for treating TAA." Studies from Guangxi Medical University Add New Findings in the Area of Genomics and Genetics (Circ 0000595 Knockdown Alleviates Cocl2-mediated Effects In Vsmcs By Regulating the Mir-582-3p/adam10 Axis) ADAM10 was confirmed as a target gene of miR-582-3p, and miR-582-3p overexpression-induced influence was almost restored by overexpressed ADAM10 in CoCl2-induced VSMCs. [Extracted from the article]

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