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Design and Implementation of a Nationwide Population-Based Longitudinal Survey of SARS-CoV-2 Infection in Spain: The ENE-COVID Study.
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- Author(s): Pastor-Barriuso, Roberto; Pérez-Gómez, Beatriz; Oteo-Iglesias, Jesús; Hernán, Miguel A.; Pérez-Olmeda, Mayte; Fernández-de-Larrea, Nerea; Molina, Marta; Fernández-García, Aurora; Martín, Mariano; Cruz, Israel; Sanmartín, José L.; León-Paniagua, José; Muñoz-Montalvo, Juan F.; Blanco, Faustino; Yotti, Raquel; Pollán, Marina
- Source:
American Journal of Public Health. May2023, Vol. 113 Issue 5, p525-532. 8p.- Subject Terms:
- Source:
- Additional Information
- Subject Terms:
- Abstract: Data System. The Spanish National Seroepidemiological Survey of SARS-CoV-2 (or ENE-COVID; SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2] is the causative agent of COVID-19) was funded by the Spanish Ministry of Health, the Instituto de Salud Carlos III, and the Spanish National Health System. Data Collection/Processing. A stratified 2-stage probability sampling was used to select a representative cohort of the noninstitutionalized population of Spain. ENE-COVID collected longitudinal data from epidemiological questionnaires and 2 SARS-CoV-2 IgG antibody tests. From April 27 to June 22, 2020, 68 287 participants (77.0% of contacted persons) received a point-of-care test and 61 095 (68.9%) also underwent a laboratory immunoassay. A second follow-up phase was conducted between November 16 and 30, 2020. Data Analysis/Dissemination. Analyses use weights to adjust for oversampling and nonresponse and account for design effects of stratification and clustering. ENE-COVID data for research purposes will be available upon request from the official study Web page. Public Health Implications. ENE-COVID, a nationwide population-based study, allowed monitoring seroprevalence of antibodies against SARS-CoV-2 at the national and regional levels, providing accurate figures by gender, age (from babies to nonagenarians), and selected risk factors; characterizing symptomatic and asymptomatic infections; and estimating the infection fatality risk during the first pandemic wave. (Am J Public Health. 2023;113(5):525–532. https://doi.org/10.2105/AJPH.2022.307167) [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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