New Opioids Research Reported from Wake Forest University School of Medicine (Kappa Opioid Receptors Reduce Serotonin Uptake and Escitalopram Efficacy in the Mouse Substantia Nigra Pars Reticulata).

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  • Source:
    Pain & Central Nervous System Week; 3/3/2023, p1379-1379, 1p
  • Additional Information
    • Abstract:
      Keywords: Antidepressants; Autacoids; Biogenic Amines; Biological Factors; Brain; Brain Stem; Central Nervous System; Drugs and Therapies; Escitalopram Therapy; G-Protein-Coupled Receptors; Health and Medicine; Membrane Proteins; Neurology; Neuropeptide Receptors; Opiate Receptors; Opioid Receptors; Opioids; Organic Chemicals; Pharmaceuticals; Psychotherapeutic Agents; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Uptake Inhibitors; Substantia Nigra; Tegmentum Mesencephali; Tryptamines; kappa Receptors EN Antidepressants Autacoids Biogenic Amines Biological Factors Brain Brain Stem Central Nervous System Drugs and Therapies Escitalopram Therapy G-Protein-Coupled Receptors Health and Medicine Membrane Proteins Neurology Neuropeptide Receptors Opiate Receptors Opioid Receptors Opioids Organic Chemicals Pharmaceuticals Psychotherapeutic Agents Selective Serotonin Reuptake Inhibitors Serotonin Serotonin Uptake Inhibitors Substantia Nigra Tegmentum Mesencephali Tryptamines kappa Receptors 2023 MAR 3 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on opioids. Here, we show that the KOR influences serotonin signaling in the SNr in multiple ways and short-term activation of the KOR alters serotonin responses to escitalopram.". [Extracted from the article]
    • Abstract:
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