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Clinical presentation of COVID‐19 and association with outcomes among hospitalized older adults.
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- Author(s): Ohuabunwa, Ugochi; Afolabi, Phebe; Tom‐Aba, Daniel; Fluker, Shelly‐Ann
- Source:
Journal of the American Geriatrics Society. Feb2023, Vol. 71 Issue 2, p599-608. 10p. - Source:
- Additional Information
- Subject Terms:
- Abstract: Background: Older adults from racial and ethnic minority groups are at higher risk for worse outcomes with COVID‐19. This study sought to characterize the symptomatology of COVID‐19 and the association of symptoms with all‐cause in‐hospital mortality and respiratory failure in a cohort of older, predominantly African American adults admitted to a tertiary hospital. Methods: A retrospective chart review of all hospitalized patients 65 and older with a positive SARS‐CoV‐2 test was conducted in a 953‐bed academic, urban hospital. Measurements included demographics, symptoms, laboratory findings, and outcomes. The primary outcome was in‐hospital mortality, and the secondary outcome was respiratory failure. Results: A total of 134 patients with a mean age of 76.4 years were studied. Fifty‐six percent were men and 90% were African American. Of these, 108 patients presented with typical symptoms, among whom 89.8% had co‐existing geriatric syndromes. Only 10.2% presented with typical symptoms alone. The most common typical symptoms were fever (57%), shortness of breath (SOB) (51.2%), and cough (48.8%). Atypical symptoms were present in 68 (51%) patients, of whom 83.8% had co‐existing typical symptoms and 76.5% had co‐existing geriatric syndromes. Only 17.2% of patients presented with atypical symptoms alone. Atypical symptoms identified were anorexia (43%), dizziness (12.4%), and syncope (7.4%). Geriatric syndromes were identified in 102 (76%) patients, including altered mental status (71.1%), weakness (26.4%), and falls (24.8%). Respiratory failure occurred in 65.8% of patients, with 35.4% requiring ventilators while 22.3% of patients died. Age, male gender, SOB, sepsis, and certain laboratory values were associated with outcomes. Conclusion: Hospitalized older adults infected with SARS‐CoV‐2 may present with a range of symptoms encompassing typical, atypical, and geriatric syndromes. Early testing for COVID‐19 should be considered in hospitalized older adults. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of the American Geriatrics Society is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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