Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T‐cell lymphoma resembling pemphigus vulgaris.

2 Geller S, Myskowski PL, Pulitzer M. NK/T-cell lymphoma, nasal type, T-cell lymphoma, and CD8-positive epidermotropic T-cell lymphoma - clinical and histopathologic features, differential diagnosis, and treatment. Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma resembling pemphigus vulgaris Dear Editor, Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma (PCAE-TCL) is an exceedingly rare and distinct cutaneous lymphoma characterized by aggressive epidermal proliferation of CD8+ T cells with rapid bullous ulceration and keratinocyte necrosis.1-3 In this report, we describe a patient with PCAE-TCL with rapid progression from a solitary chest lesion to near-to-full-body coverage in 4 weeks. [Extracted from the article]

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