Multiple antimicrobial resistant Salmonella enterica serovar Paratyphi B variant Java in cattle: a case report.

Publisher: Wiley Country of Publication: England NLM ID: 0031164 Publication Model: Print Cited Medium: Print ISSN: 0042-4900 (Print) Linking ISSN: 00424900 NLM ISO Abbreviation: Vet Rec Subsets: MEDLINE

Publication: 2021- : [Oxford] : Wiley
Original Publication: -June 2009 : London : British Veterinary Medicine

Anti-Bacterial Agents/*pharmacology ; Cattle Diseases/*drug therapy ; Paratyphoid Fever/*veterinary ; Salmonella paratyphi B/*drug effects; Animals ; Anti-Bacterial Agents/therapeutic use ; Cattle ; Cattle Diseases/microbiology ; Colony Count, Microbial/veterinary ; Dairying/methods ; Disease Outbreaks/veterinary ; Drug Resistance, Bacterial ; Drug Resistance, Multiple, Bacterial ; Female ; Microbial Sensitivity Tests/veterinary ; Paratyphoid Fever/drug therapy ; Paratyphoid Fever/microbiology ; Polymerase Chain Reaction/veterinary ; Risk Management ; Salmonella paratyphi B/genetics ; Salmonella paratyphi B/isolation & purification ; United Kingdom

An epidemiological investigation of a calf rearing premises and a closely associated dairy herd was carried out after the isolation of Salmonella enterica serovar Paratyphi B variant Java phage type 3b variant 2 from clinically diseased calves on the premises. The isolate was resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides, tetracyclines, trimethoprim and cefoperazone. The organism was widespread on the calf unit and was also recovered from the dairy premises, mainly from groups of weaned calves. The investigation was extended to 10 epidemiologically linked farms but no S Java was isolated from any of the 40 to 60 samples collected from each premises. Molecular studies showed that the S Java isolates were genetically most similar to isolates from cases of human disease associated with ornamental fish tanks or feed. Long PCR and resistance gene profiling identified a resistance island which was indistinguishable from the human 'fish tank' strain of S Java and animal and human epidemic strains of S Typhimurium DT104. The isolates were clearly distinguished from multi-resistant S Java strains commonly associated with continental poultry. This is the first report of S Java with this resistance pattern in Great Britain.

0 (Anti-Bacterial Agents)

Date Created: 20050326 Date Completed: 20050421 Latest Revision: 20190702

20231215

10.1136/vr.156.11.343

15789647