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Effects of Neural Mobilization on Pain Intensity, Disability, and Mechanosensitivity: An Umbrella Review With Meta–Meta-Analysis.
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- Author(s): Cuenca-Martínez, Ferran; Touche, Roy La; Varangot-Reille, Clovis; Sardinoux, Maëva; Bahier, Jade; Suso-Martí, Luis; Fernández-Carnero, Josué
- Source:
PTJ: Physical Therapy & Rehabilitation Journal. Jun2022, Vol. 102 Issue 6, p1-8. 8p. - Source:
- Additional Information
- Subject Terms: MUSCULOSKELETAL system diseases; ONLINE information services; MEDICAL databases; PAIN measurement; META-analysis; CONFIDENCE intervals; MEDICAL information storage & retrieval systems; SYSTEMATIC reviews; PHYSICAL therapy; FUNCTIONAL assessment; TREATMENT effectiveness; MANIPULATION therapy; DESCRIPTIVE statistics; MEDLINE; DATA analysis software; PAIN management; EVALUATION
- Abstract: Objective The purpose of this study was to assess the current evidence for the effects of neural mobilization (NM) treatments. Methods Three umbrella reviews with meta–meta-analyses were conducted to determine the effects of NM on pain intensity and disability in people with musculoskeletal disorders and on mechanosensitivity in participants who were asymptomatic. The study used the grading criteria proposed by the Physical Activity Guidelines Advisory Committee to assess the quality of evidence. Results One meta–meta-analysis revealed a statistically significant moderate effect on pain intensity (standardized mean difference [SMD] = −0.75, 95% CI = −1.12 to −0.38) but with evidence of heterogeneity (Q = 14.13; I2 = 65%). The study found a significantly large effect of NM on disability (SMD = −1.22, 95% CI = −2.19 to −0.26), again with evidence of heterogeneity (Q = 31.57; I2 = 87%). The third meta–meta-analysis showed a statistically significant moderate effect of NM on mechanosensitivity (SMD = 0.96, 95% CI = 0.35 to 1.57), with no evidence of heterogeneity (Q = 2.73; I2 = 63%). For all examined outcomes, the quality of evidence was limited. Conclusion Overall, the results indicated that although NM treatment had a moderate to large beneficial clinical effect on pain intensity and disability in people with musculoskeletal disorders and on mechanosensitivity in individuals who were asymptomatic, the quality of evidence was limited. Impact Neural mobilization treatments showed positive results on the pain intensity and disability in individuals with musculoskeletal conditions. Neural mobilization could be integrated into the physical therapy management, although more research is needed. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of PTJ: Physical Therapy & Rehabilitation Journal is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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