ORALNE MANIFESTACIJE KOD PACIJENATA OBOLELIH OD KOVIDA-19. (Bosnian)

ORAL MANIFESTATIONS IN PATIENTS INFECTED WITH COVID-19. (English)

Introduction:In addition to the characteristic clinical picture of respiratory infection, patients with COVID-19 can also be diagnosed with oral manifestations. Aim: The aim of this study was to review current literature for the prevalence of changes in the oral cavity i.e., the presence of oral symptoms in patients with COVID-19, in order to indicate that oral manifestations may occur due to viral infection with SARS-CoV-2. Methods: Important information relevant to the study was obtained by searching the available electronic PubMed and Google Scholar database. Results: Oral lesions were found in different locations in patients with COVID-19: tongue mucosa (dorsum and lateral sides of the tongue), buccal mucosa, hard and soft palate, inner lip and gingiva. The most common were ulcerations in different parts of the oral cavity. It is still unclear whether oral lesions in SARS-CoV-2 virus infection were a consequence of the primary effect of the virus itself or a secondary manifestation of the infection. The high presence of angiotensin-converting enzyme 2 in oral epithelial cells of the tongue and salivary glands indicates that the oral cavity may be particularly susceptible to SARS-CoV-2 infection. Taste disorder is the most common oral symptom in patients with COVID-19. Conclusion: Oral lesions, xerostomia, taste disorders can occur in patients diagnosed with COVID-19. Therefore, a comprehensive intraoral examination is necessary in order to determine changes in the oral cavity and apply proper treatment. [ABSTRACT FROM AUTHOR]

Uvod:Kod pacijenata obolelih od KOVID 19, se pored karakteristične kliničke slike respiratorne infekcije, mogu se dijagnostikovati i oralne manifestacije. Cilj: Cilj rada je bio da se pregledom savremene literature sagleda zastupljenost promena u usnoj duplji odnosno prisustvo oralnih simptoma kod obolelih od KOVID-19, kako bi se ukazalo da oralne manifestacije mogu nastati usled virusne infekcije SARS-CoV-2. Metode: Do relevantnih informacija koje su bitne za rad, došli smo pretragom dostupne elektronske baze podataka PubMed-a i Google Scholar. Rezultati: Utvrđena je raznovrsna lokalizacija oralnih lezija kod obolelih od KOVID-19: sluzokoža jezika (dorzuma i bočne strane jezika), bukalna sluzokoža, tvrdo i meko nepce, unutrašnja strana usana i gingive. Najčešće su evidentirane ulceracije u različitim delovima usne duplje. Još uvek je kontraverzno pitanje da li su oralne lezije kod infekcije SARS-CoV-2 virusa nastale kao posledica primarnog dejstva samog virusa ili kao sekundarna manifestacija infekcije. Visoka zastupljenost receptora za angiotenzin-konvertujući enzim 2 na oralnim epitelnim ćelijama jezika i pljuvačnih žlezdi ukazuje da usna duplja može biti posebno podložna infekciji SARS-CoV-2. Disfunkcija čula ukusa je najčešći oralni simptom kod pacijenata obolelih od KOVID-19. Zaključak: Oralne lezije, kserostomija, poremećaji čula ukusa mogu se javiti kod pacijenata kod kojih je dijagnostikovana infekcija KOVID-19, zbog čega je bitno načiniti iscrpan intraoralni pregled da bi se utvrdile promene u usnoj duplji i primenila adekvatna terapija. [ABSTRACT FROM AUTHOR]

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