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Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
West Ashley Library
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Phone: (843) 766-6635
Wando Mount Pleasant Library
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Phone: (843) 805-6888
Village Library
9 a.m. - 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. - 6 p.m.
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Otranto Road Library
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McClellanville Library
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Keith Summey North Charleston Library
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John's Island Library
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Hurd/St. Andrews Library
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Main Library
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Phone: (843) 805-6930
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Antibiotics for Fever Among Children: Findings From the Surveillance for Enteric Fever in India Cohorts.
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- Author(s): Karthikeyan, Arun S; Srinivasan, Manikandan; Kanungo, Suman; Sinha, Bireshwar; Shrivastava, Ankita; Ramanujam, Karthikeyan; Ganesan, Santhosh Kumar; Subramaniam, Sathyapriya; Sindhu, Kulandaipalayam Natarajan; Krishna, Swathi; Samuel, Prasanna; Rose, Winsley; Mohan, Venkata Raghava; Veeraraghavan, Balaji; Rongsen-Chandola, Temsunaro; Dutta, Shanta; Bavdekar, Ashish; John, Jacob; Kang, Gagandeep
- Source:
Journal of Infectious Diseases; 2021 Supplement, Vol. 224, pS494-S501, 8p- Subject Terms:
- Source:
- Additional Information
- Subject Terms:
- Abstract:
Background: Acute febrile illness in children is frequently treated with antibiotics. However, the inappropriate use of antibiotics has led to the emergence of multidrug-resistant pathogens.Methods: We measured use of antibiotics for fever in 4 pediatric cohorts that were part of the Surveillance for Enteric Fever in India (SEFI) network. In this network, 24 062 children were followed up weekly, capturing information on fever and other morbidity between October 2017 and December 2019.Results: An antibiotic was given in 27 183 of the 76 027 (35.8%) episodes of fever. The incidence of fever-related antibiotic use was 58.0 (95% confidence interval [CI], 57.2-58.6) per 100 child-years. The median time to initiation of antibiotics was 4 days, and in 65% of those who received an antibiotic it was initiated by the second day. Antibiotics were continued for <3 days in 24% of the episodes. Higher temperature, younger age, male sex, joint family, higher education, internet access, and availability of personal conveyance were associated with antibiotic treatment for fever.Conclusions: In developing countries where antibiotic use is not regulated, broad-spectrum antibiotics are initiated early, and often inappropriately, in febrile illness. Frequent and inappropriate use of antibiotics may increase risk of antimicrobial resistance. [ABSTRACT FROM AUTHOR] - Abstract: Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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