Characterization of a common progenitor pool of the epicardium and myocardium.

GENE regulatory networks; PROGENITOR cells; PARACRINE mechanisms; HEART; HEART cells

The article presents the discussion on providing unified transcriptional and anatomical definition of cardiac progenitor types. Topics include epicardium provides important paracrine signals and generating several cardiac cell types; and characterizing the various cell types of the embryonic heart and generating hypotheses about the origin and fate.