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John L. Dart Library
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West Ashley Library
9 a.m. – 7 p.m.
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Folly Beach Library
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Wando Mount Pleasant Library
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Effects of Transcranial Direct Current Stimulation for Treatment of Primary Dysmenorrhea: Preliminary Results of a Randomized Sham-Controlled Trial.
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- Author(s): Pegado, Rodrigo; Silva, Luana Karyne; Dantas, Hégila da Silva; Câmara, Hialison Andrade; Mescouto, Karime Andrade; Silva-Filho, Edson Meneses; Lopes, Johnnatas Mikael; Micussi, Maria Thereza Albuquerque Barbosa Cabral; Correia, Grasiéla Nascimento
- Source:
Pain Medicine; Dec2020, Vol. 21 Issue 12, p3615-3623, 9p- Subject Terms:
TREATMENT of dysmenorrhea; AFFECT (Psychology); CHI-squared test; COMPARATIVE studies; GRIP strength; LIFE skills; MENSTRUAL cycle; QUESTIONNAIRES; PAIN management; MCGILL Pain Questionnaire; PAIN measurement; BODY movement; RANDOMIZED controlled trials; TREATMENT effectiveness; PRE-tests & post-tests; BLIND experiment; SEVERITY of illness index; DESCRIPTIVE statistics; TRANSCRANIAL direct current stimulation - Source:
- Additional Information
- Abstract: Objective The aim of this trial was to investigate the effects of five consecutive sessions of anodal transcranial direct current stimulation (tDCS) over the motor cortex (M1) on pain, mood, and physical performance in patients with primary dysmenorrhea (PDM). Design This is a double-blind randomized controlled trial. Subjects Twenty-two participants with PDM according to the No. 345-PDM Consensus Guideline were included. Methods Eleven active treatment and 11 sham stimulation patients received five applications over a one-week period. The primary outcome measures were pain evaluated by numeric rating scale (NRS) and McGill Questionnaire score. Secondary outcomes measures were responses to the Positive and Negative Affect Schedule (PANAS), Hamilton Anxiety Scale (HAM-A), grip strength, and six-minute walk test (6MWT). Baseline data were performed during the first menstrual cycle, and during the second menstrual cycle, participants were conducted to tDCS treatment, and postintervention data were collected. Results The intervention provided significant improvements on NRS in active tDCS, shown as an interaction between group intervention vs pre/postintervention vs days of menstrual cycle (Wald x2 = 10.54, P = 0.005), main effect of days of menstrual cycle (Wald x2 = 25.42, P < 0.001), and pre/postintervention (Wald x2 = 6.97, P = 0.008). McGill showed an interaction effect between pre/postintervention and group of stimulation (Wald x2 = 18.45, P = 0.001), with a large reduction in active tDCS (P < 0.001, d = 0.75). Psychological and functional outcomes did not differ between groups or pre/postintervention. Conclusions tDCS could provide pain relief in subjects with PDM. These results provide some preliminary evidence for the potential role of tDCS as a contributor to the management of symptoms of PDM. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Pain Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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